Diphenhydramine overdose case study

Diphenhydramine - Uses, Dosage, Side Effects, Overdose

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Diphenhydramine overdose. Diphenhydramine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. In case of diphenhydramine overdose, get medical help or contact a Poison Control Center helpline at …

Diphenhydramine - Uses, Dosage, Side Effects, Overdose

Diphenhydramine overdose - connection.ebscohost.com

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Related Articles. Diphenhydramine overdose. // Reactions Weekly;Aug2015, Vol. 1563 Issue 1, p82 . The article presents a case study of a 30-year-old woman who experienced seizures, tachycardia and cardiovascular collapse after taking a high dosage of diphenhydramine for an attempted suicide.

Diphenhydramine overdose - connection.ebscohost.com

Diphenhydramine Overdose with Intraventricular Conduction ...

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9/19/2014 · Diphenhydramine toxicity commonly manifests with antimuscarinic features, including dry mucous membranes, tachycardia, urinary retention, mydriasis, tachycardia, and encephalopathy. Severe toxicity can include seizures and intraventricular conduction delay. We present here a …

Diphenhydramine Overdose with Intraventricular Conduction ...

Diphenhydramine Overdose with Intraventricular Conduction ...

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Diphenhydramine Overdose Related Delirium: A Case Report ... and placebo in this double-blind crossover study. Diphenhydramine plasma concentrations and central nervous system actions were ...

Diphenhydramine Overdose with Intraventricular Conduction ...

Diphenhydramine Overdose Related Delirium: A Case Report

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Seldom considered to be a drug that causes renal problems, diphenhydramine can have adverse effects in some patients, as illustrated by a case study of a middle-aged veteran. Extra precautions are urged before this medication is prescribed, especially in elderly patients.

Diphenhydramine Overdose Related Delirium: A Case Report

Diphenhydramine and Acute Kidney Injury | P&T Community

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In one case, hemodialysis and ultrafiltration were performed which had only limited effect on diphenhydramine plasma elimination kinetics. This patient died of …

Diphenhydramine and Acute Kidney Injury | P&T Community

Diphenhydramine Suicide--Case Report - ResearchGate

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Diphenhydramine overdose can cause central nervous system, anticholinergic, and cardiovascular effects. In addition to inhibition of cardiac fast sodium channels, higher concentrations of the drug also inhibit potassium channels, which can result in QT interval prolongation. ... In a recent case control study (Gilboa 2009), ...

Diphenhydramine Suicide--Case Report - ResearchGate

Diphenhydramine - an overview | ScienceDirect Topics

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Garry M. Walsh, in Side Effects of Drugs Annual, 2010 Drug overdose. Diphenhydramine is included in many over-the-counter formulations for the treatment of allergic disease, insomnia, and symptoms of the common cold. Such medications are often used in children, with the consequential risk of unintended diphenhydramine overdose. In a retrospective review of 25 012 cases of acute diphenhydramine ...

Diphenhydramine - an overview | ScienceDirect Topics

Diphenhydramine - an overview | ScienceDirect Topics

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Background: Diphenhydramine (DPHM) overdose is a frequent cause of acute poisoning. Although its clinical features are well known, information about the dose dependent toxicity of DPHM is still scarce. The objective of this study was to investigate the dose-dependent toxicity of DPHM in patients with acute DPHM poisoning.Methods: We have analyzed retrospectively all well-documented cases with ...

Diphenhydramine - an overview | ScienceDirect Topics

Dose-dependent toxicity of diphenhydramine overdose - D ...

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The article presents case report on the death of five people due to drug overdose involving lidocaine, diamorphine, and dextromethorphan. The real risk of acetaminophen overdose. Wall, Chris // RN;Aug85, Vol. 48 Issue 8, p35 . Discusses the hazards of acetaminophen overdose.

Dose-dependent toxicity of diphenhydramine overdose - D ...

Dextromethorphan/diphenhydramine overdose

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The case study presented illustrates an example of diphenhydramine-induced renal disease in a middle-aged veteran. Antihistamines with anticholinergic properties can cause postrenal obstruction, resulting in delayed bladder emptying. This can result in urine accumulation and lead to increased pressure and a …

Dextromethorphan/diphenhydramine overdose

Diphenhydramine and Acute Kidney Injury

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6/25/2018 · Diphenhydramine (DPH), a first generation H1 histamine receptor antagonist, is widely used as an over‐the‐counter (OTC) drug; therefore, the frequency of its overdose is high. However, cardiac arrest due to overdose is rare because of its wide therapeutic range.

Diphenhydramine and Acute Kidney Injury

Cardiac arrest caused by diphenhydramine overdose ...

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We will present a case in which the usual modalities fbr type la antiamhythmic toxicity were unsuccessful in treating a diphenhydramine cardiotoxicity but phenytoin was. We will then review the literature and discuss the use of phenytoin in treating type la antiarrhythmic toxicity. Case Study

Cardiac arrest caused by diphenhydramine overdose ...

Treatment of Diphenhydramine Cardiac Toxicity with ...

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Diphenhydramine is an antihistamine mainly used to treat allergies. It is also used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea. It is used by mouth, injection into a vein, and injection into a muscle. Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours.

Treatment of Diphenhydramine Cardiac Toxicity with ...

Diphenhydramine - Wikipedia

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Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.

Diphenhydramine - Wikipedia

Diphenhydramine overdose | Multimedia Encyclopedia ...

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In one case, hemodialysis and ultrafiltration were performed which had only limited effect on diphenhydramine plasma elimination kinetics. This patient died of diphenhydramine overdose and extreme hypothermia. All intoxications except the one mentioned before had an uncomplicated clinical course. In vitro experiments indicate that ...

Diphenhydramine overdose | Multimedia Encyclopedia ...

Clinical Symptomatology of Diphenhydramine Overdose: An ...

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1/15/2019 · Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 Apr 2019), Cerner Multum™ (updated 1 Apr 2019), Wolters Kluwer™ …

Clinical Symptomatology of Diphenhydramine Overdose: An ...

Diphenhydramine Use During Pregnancy | Drugs.com

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These doses are similar is consistent with previous case reports describing the to a recent study (126 patients) with QT prolonga- occurrence of seizures and coma in patients with tions after minimal DPHM ingestions of 0.5 g.16 DPHM overdose above 1.0 g.1""12 To our knowledge However, neither in this nor in the previous study only one patient ...

Diphenhydramine Use During Pregnancy | Drugs.com

(PDF) Dose-dependent toxicity of diphenhydramine overdose ...

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What the study found. A team led by Shelley Gray, a pharmacist at the University of Washington’s School of Pharmacy, tracked nearly 3,500 men and women ages 65 and older who took part in Adult Changes in Thought (ACT), a long-term study conducted by the University of Washington and Group Health, a Seattle healthcare system.

(PDF) Dose-dependent toxicity of diphenhydramine overdose ...

Common anticholinergic drugs like ... - Harvard Health Blog

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8/18/2011 · Therefore, an overdose of diphenhydramine might stimulate 5HT1A and 2A but not 3 receptors as the present case did not show diarrhea. Further case investigation is needed to explore correlations between an overdose of diphenhydramine and serotonin‐related symptoms.

Common anticholinergic drugs like ... - Harvard Health Blog

Diphenhydramine overdose mimicking serotonin syndrome ...

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3/1/2019 · Diphenhydramine hydrochloride is an antihistamine drug having the chemical name 2-(diphenylmethoxy)-N,N -dimethylethylamine hydrochloride and has the molecular formula C 17 H 21 NO•HCI (molecular weight 291.82). It occurs as a white odorless, crystalline powder and is freely soluble in water and alcohol.

Diphenhydramine overdose mimicking serotonin syndrome ...
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